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Melasma and photoaging present distinct challenges: pigment deposits require targeted melanin fragmentation, while wrinkles and laxity demand collagen remodeling. Combination laser protocols now address both concerns simultaneously using calibrated wavelengths and treatment sequencing. Key Takeaways Q-switched lasers (1064 nm, 532 nm) fragment melanin deposits without thermal damage, making them key for melasma clearance in darker skin types [1] Fractional lasers (non-ablativ